Pdf bridelia ferruginea is commonly used in traditional african medicine tam for. Evaluation of antidiabetic role of bridelia ferruginea. The leaves, leafy twigs and bark are all employed, and the medical activity is believed to be mainly due to the presence of tannins which are astringent and saponosides332. A shrub or straggly tree to 15 m high with crooked bole up to 1. Bridelia retusa is a species of bridelia found in bangladesh, nepal, india, sri lanka, southern china, indochina, thailand and sumatra this is the commonest indian species of bridelia, found in dry deciduous to moist deciduous forests, mixed forest, riverbanks, rocky places, up to 2000 m in south india, 600 m in central and centraleast india, 1600 m on himalayas and m in north east india. Acute and subchronic 28 days oral toxicity evaluation. Zone of inhibition around extract ranged from 10 to 25 mm in diameter. Citeseerx document details isaac councill, lee giles, pradeep teregowda. The methanol leaf extract of bridelia ferruginea exhibited hypoglycaemic effect in glucoseintolerant rats. Pdf bridelia ferruginea produces antineuroinflammatory activity. Subchronic toxicity studies of the aqueous stem bark. Nov 23, 2019 bridelia ferruginea pdf posted on november 23, 2019 by admin learn more about bridelia uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain bridelia.
All structured data from the file and property namespaces is available under the creative commons cc0 license. Bridelia ferruginea euphorbiaceae is a shrub or straggly tree of about 15m high with crooked bole and an up to 1. Bridelia ferruginea produces antineuroinflammatory. Toxicological evaluation of the aqueous stem bark extract of. Phytochemical study and biological activities of hydroalcoholic extract of the leaves of bridelia ferruginea benth and its fractions.
The parameter which was taken account during the experimentation was total urine volume. The stembark aqueous extract of bridelia ferruginea was found to be. Inhibitory potentials of phenolicrich extracts from. The animals were observed for mortality and clinical signs for 3 h. Pdf effects of aqueous extract of bridelia ferruginea stem bark on. Experimental materials stem bark, leaves and fruits of bf, distilled water, and acacia gum bdh, england were used in the study, all other reagents were of analytical grade and used without further purification. Bridelia is a plant genus of the family phyllanthaceae first described as a genus in 1806. Kirni, kimi hausa, maren fulani, iralodan yoruba, and oha, ede, ola in igbo.
Effect of bridelia ferruginea euphorbiaceae leaf extract on. Pharmacists also advise patients not to drink alcohol with. Text is available under the creative commons attributionsharealike license. After 2 weeks on these diets, oral glucose tolerance test showed that sucrose feeding significantly impaired glucose homeostasis 1 and 2 hours after a glucose challenge 76. The bark of bridelia micrantha is used to treat burns, wounds, venereal diseases, tapeworm, diarrhoea and toothache. Uses, side effects, interactions, dosage, and warning. Bridelia retusa is a deciduous, large shrub or tree, usually growing up to 10 metres tall but occasionally to 20 metres. Pdf a retrospective clinical study on the effectiveness of. Isolation and characterization of flavonoids chalcones. One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your bloodpressure extensively.
Citeseerx bridelia ferruginea correspondence to author. Chemical and biological studies on bridelia ferruginea grown. Effects of stem bark and leaf extracts of bridelia ferruginea on skeletal muscle. The present investigation was carried out to evaluate the safety of hydroethanol extract of bridelia ferruginea benth euphorbiaceae root bark. Toxicological evaluation of the aqueous stem bark extract. For acute toxicity study, a single dose of 2000 and 5000 mgkg of the b. The plant list includes 141 scientific plant names of species rank for the genus bridelia.
Pharmaceutical characterization of aqueous stem bark. Qualitative and quantitative analyses of bridelia ferrugineastem bark indicated the presence of alkaloids, flavonoids, steroids, cardiac glycosides, tannins, saponins and phenols. Assessment of bridelia ferruginea benth for its therapeutic potential in pregnancyinduced impaired glucose tolerance in rats. This page was last edited on 12 december 2019, at 17. It is commonly found in the savannah and its common names in nigeria include. Introduction diabetes mellitus dm is one of the most severe.
Bridelia ferruginea euphorbiaceae traditionnaly used by traditional healers is a shrub from 1 to 8 cm. Pdf effects of aqueous extract of bridelia ferruginea. Pdf assessment of bridelia ferruginea benth for its. The parameter which was taken account during the experimentation was total. Subchronic toxicity studies of the aqueous stem bark extract. Thus, the authors validated the activity both for fungal and bacterial agents of the crude extract obtained by boiling of the ripe stem bark of b. Asas, assas, bridelia cathartica, bridelia ferruginea, bridelia grandis, bridelia micrantha, bridelia. Male wistar rats, aged 6 7 weeks and weighing 140 160 g, were used. Effect of bridelia ferruginea euphorbiaceae leaf extract. Pdf a retrospective clinical study on the effectiveness. Bridelia ferruginea stem bark against plasmodium berghei berghei in mice.
To evaluate the hypoglycaemic effect of the methanol extract of bridelia ferruginea leaves mebf on sucroseinduced glucose intolerance in rats. Cytotoxic constituents of the terrestrial plant bridelia ferruginea were isolated. According to world health organization, 80% of the world population still relies mainly on plant drugs. Effect of an aqueous extract of bridelia ferruginea benth euphorbiaceae on the isolated aorta of guinea pig. Effects of the aqueous extract of bridelia ferruginea stem bark on carrageenaninduced oedema and granuloma tissue formation in rats and mice. Acute and subchronic 28 days oral toxicity evaluation of. Phytochemical and acute toxicity study of bridelia ferruginea extracts were done to determine the secondary metabolites and toxicity level of the plant. Inhibitory potentials of phenolicrich extracts from bridelia. Bridelia ferruginea wikispecies, free species directory. Useful tropical plants database 2014 by ken fern, web interface by ajna fern with help from richard morris.
Data from patients visiting the clinic of the cpmr between may 2012 and may 20 were retrieved for analysis. Pdf effect of bridelia ferruginea euphorbiaceae leaf extract on. Traditional antimalarials and the develop ment of novel. This page was last edited on 9 december 2019, at 15. Pdf effects of aqueous extract of bridelia ferruginea benth. Bridelia ferruginea b dye was extracted from the bark of the tree using aqueous extraction method. Epigallocatechin egc and epigallocatechin gallate egcg isolated from b. Pdf effect of an aqueous extract of bridelia ferruginea. Tea made from the pulped bark is used for fevers, headaches, stiffness, and rheumatic pains and as a local application for treating oedemas 4. The experiments were carried out under the same conditions with synthetic pharmacological diuretics furosemide, hydrochlorothiazide, and spironolactone. These results suggest that catechins constituents from b.
Anticandidal effect of extract of bridelia s tipularis. Euphorbiaceae is a shrub which is employed in tam for treating arthritis and as an embrocation for the treatment of bruises, boils, dislocation, and burns 2, 3. Grey cotton %used was obtained from oja oba market, at akure south local government, akure, ondo state, nigeria. Bridelia ferruginea euphorbiaceae is a shrub commonly growing up to a height of 45. Fasting glucose concentrations ranged from 45 to 70 mgdl, and the increase was significant in the sucrose diet groups from week 1. The plant list includes a further 77 scientific plant names of infraspecific rank for the genus bridelia. Despite all these uses, extensive toxicological evaluation has not been carried out. Phytochemical study and biological activities of hydro. The present study was carried out to evaluate the antidiabetic activity of catechins isolated from bridelia ferruginea in previous studies. The effects of an aqueous extract of bridelia ferruginea stembark sea have been evaluated on on the elimination of the water overlaod in male rat. Extracted dye was used to dye cellulosic cotton fabric in presence of 5% calcium chloride cacl2 or 5% alum kalso4212h2o of weight of fabric o. Sep 30, 2014 this page was last edited on 9 december 2019, at 15. The record derives from wcsp data supplied on 20120323 which reports it as an accepted name record 24516 with original publication details. West african plants a photo guide bridelia ferruginea benth.
Bridelia ferruginea is commonly used in traditional african medicine tam for treating various inflammatory conditions. Bridelia ferruginea, epigallocatechin, streptozotocin, diabetes, medicinal plant. The supporting information is available free of charge on the acs. Bridelia ferruginea usages, effets secondaires, avis. At the high dose 400 mgkg of bridelia ferruginea, there was a significant decrease p bridelia ferruginea is an indigenous medicinal species in nigeria. Bakoma b, sanvee s, metowogo k, potchoo y, gadegbeku ke, aklikokou k, et al.
Bridelia ferruginea produces antineuroinflammatory activity through. Bridelia ferruginea is a popular herbal remedy in parts of africa, and the bark is commonly sold in local markets. Figure 1 the effect bridelia ferruginea methanol leaf extract on blood sugar level. We do not intend the plant list to be complete for names of infraspecific rank. The antifungal, antimicrobial, antioxidant and cytotoxic activities of methylene chloride, methanol and hydroethanolic extracts of the leaves of bridelia ferruginea and sterm bark of pteleopsis suberosa were investigated against six gram positive and gram negative strains bacteria and six.
Effects of stem bark and leaf extracts of bridelia ferruginea on rat bladder smooth muscle. Files are available under licenses specified on their description page. If you experience drowsiness, dizziness, hypotension or a headache as sideeffects when using bridelia ferruginea medicine then it may not be safe to drive a vehicle or operate heavy machinery. Bridelia ferruginea did not modify hematological parameters significantly p0.
It is also used for the treatment of diabetes, arthritis and boils. At the high dose 400 mgkg of bridelia ferruginea, there was a significant decrease p free radicals which is. The extract did not modify significantly, the lipid profile, kidney and liver function parameters. The total flavonoid contents in free and bound phenolicrich extracts of bridelia ferruginea. Decoction of its stem, bark and leaves are used in the treatment of different ailments and for other commercial purposes.
Bridelia ferruginea euphorbiaceae traditionnaly used by. Fabric dyed without mordant was lighter in hue than metal ion mordanted dyed fabrics. May 04, 2020 bridelia ferruginea pdf learn more about bridelia uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain bridelia. Color and fastness properties of mordanted bridelia. Abstractphytochemical investigation of the methanolic extract of dried leaves of bridelia ferruginea led to the isolation and identification of fourteen compounds 114. The total phenolic contents in free and bound phenolicrich extracts of bridelia ferruginea. West african plants a photo guide bridelia ferruginea. The product is prepared from the dried leaves of bridelia ferruginea.
The leaves, leafy twigs and bark are all employed, and the medical activity is believed to be mainly due to the presence of tannins which are astringent and saponosides. Phytochemistryand acute toxicity study of bridelia. Bridelia ferruginea b tree bark was obtained from itaoniyan farm plantation, o. Catechins as antidiabetic compounds of bridelia ferruginea. Extracts from the plant have been shown to exhibit antiinflammatory property in a number of in vivo models. The aim of the present investigation was to evaluate the subchronic toxicological effects of the stem bark aqueous extract of bridelia.
Cytotoxic constituents of the terrestrial plant bridelia ferruginea were isolated using bioactivityguided fractionation, which revealed the presence of the previously known deoxypodophyllotoxin 1, isopicrodeoxypodophyllotoxin 2. The efficacy of bridelia ferruginea benth bark extract in wastewater treatment. Toxicological evaluation of the aqueous stem bark extract of bridelia. Chalcones and anthocyanidines represents essential groups of natural products which possess wide range of pharmacological activity such as antibacterial, antitumor, anticancer, antitubercular, antiinflammatory, antioxidant and antimalarial properties. From the ethanolic extract of the leaves of bridelia ferruginea benth, two flavonoids bioactive compounds 6, 4l dihydroxy 3l propen chalcones. Root is used to treat stomach pains, possibly gastric ulcers, or can be powdered and mixed with fat or oil and rubbed into the head to cure headaches. Bridelia ferruginea wikispecies wikispecies, free species. Bridelia ferruginea is a woody shrub that grows in the savannah or rain forests of africa and has traditionally been used to treat diabetes, arthritis and boils. Bridelia ferruginea produces antineuroinflammatory activity. It has different local names given to it by different tribes such as kirni hausa, iralodan yoruba, ola igbo, mareni fulani.
As an extension of previous podophyllotoxin research, sar studies. Bridelia ferruginea stem bark extract in order to determine its suitability for formulation into solid dosage forms. Bridelia ferruginea is commonly used in traditional african medicine tam for. Nmr and ms spectra of compounds 14, 15a,c,d, 1728, and 3032 pdf.
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